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Cellosaurus Ishikawa 3-H-12 (CVCL_D199)

[Text version]
Cell line name Ishikawa 3-H-12
Synonyms Ishikawa-3H-12; Ishikawa-3H12; Ishikawa 3H12; Ishikawa 3 H 12; Ishikawa3-H-12; Ishikawa clone 3-H-12; Ishikawa-H-12
Accession CVCL_D199
Resource Identification Initiative To cite this cell line use: Ishikawa 3-H-12 (RRID:CVCL_D199)
Comments Population: Japanese.
Doubling time: 24.0 hours (PubMed=9183638).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
Disease Type I endometrial adenocarcinoma (NCIt: C40145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2529 (Ishikawa)
Children:
CVCL_7260 (ECC-1)CVCL_C3G7 (Ishikawa 3-H-12 PRA-14)CVCL_C3G8 (Ishikawa 3-H-12 PRB-59)
CVCL_JG52 (Ishikawa 3-H-12-Luc)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1505

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,11
D7S8209,10
D13S3179,12,13
D16S5399
TH019,10
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=9183638
Masato Nishida, Kunitake Kasahara, Akinori Oki, Toyomi Satoh, Yuko Arai, Takeshi Kubo;
Establishment of eighteen clones of Ishikawa cells.
Hum. Cell 9:109-116(1996)

DOI=10.1007/978-4-431-53981-0_2
Masato Nishida;
Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma.
(In book chapter) Cell and molecular biology of endometrial carcinoma; Kuramoto, Hiroyuki & Nishida, Masato (eds.); pp.35-58; Springer; Tokyo; Japan (2003)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Cross-references
Cell line collections (Providers) JCRB; JCRB1505
Cell line databases/resources CLO; CLO_0037230
cancercelllines; CVCL_D199
Anatomy/cell type resources BTO; BTO_0006568
Encyclopedic resources Wikidata; Q54898297
Polymorphism and mutation databases Cosmic; 871553
Cosmic; 889119
Cosmic; 1007163
Cosmic; 1066223
Cosmic; 1223489
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19