| Cell line name |
Ishikawa 3-H-12 |
| Synonyms |
Ishikawa-3H-12; Ishikawa-3H12; Ishikawa 3H12; Ishikawa 3 H 12; Ishikawa3-H-12; Ishikawa clone 3-H-12; Ishikawa-H-12 |
| Accession |
CVCL_D199 |
| Resource Identification Initiative |
To cite this cell line use: Ishikawa 3-H-12 (RRID:CVCL_D199) |
| Comments |
Population: Japanese. Doubling time: 24.0 hours (PubMed=9183638). Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
| Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
| Disease |
Type I endometrial adenocarcinoma (NCIt: C40145) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Parent: CVCL_2529 (Ishikawa) Children:
|
| Sex of cell |
Female |
| Age at sampling |
39Y |
| Category |
Cancer cell line |
| STR profile |
Source(s): JCRB=JCRB1505
Markers: Run an STR similarity search on this cell line |
| Publications | PubMed=9183638 Masato Nishida, Kunitake Kasahara, Akinori Oki, Toyomi Satoh, Yuko Arai, Takeshi Kubo; Establishment of eighteen clones of Ishikawa cells. Hum. Cell 9:109-116(1996) DOI=10.1007/978-4-431-53981-0_2 Masato Nishida; Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma. (In book chapter) Cell and molecular biology of endometrial carcinoma; Kuramoto, Hiroyuki & Nishida, Masato (eds.); pp.35-58; Springer; Tokyo; Japan (2003) PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677 Christopher T. Korch, Monique Ann Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford; DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination. Gynecol. Oncol. 127:241-248(2012) |
| Cross-references |
| Cell line collections (Providers) |
JCRB; JCRB1505
|
| Cell line databases/resources |
CLO; CLO_0037230
cancercelllines; CVCL_D199
|
| Anatomy/cell type resources |
BTO; BTO_0006568
|
| Encyclopedic resources |
Wikidata; Q54898297
|
| Polymorphism and mutation databases |
Cosmic; 871553
Cosmic; 889119
Cosmic; 1007163
Cosmic; 1066223
Cosmic; 1223489
|
| Entry history |
| Entry creation | 22-Oct-2012 |
| Last entry update | 19-Dec-2024 |
| Version number | 19 |
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