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Cellosaurus Ishikawa 3-H-12 (CVCL_D199)

[Text version]

Cell line name Ishikawa 3-H-12
Synonyms Ishikawa-3H-12; Ishikawa-3H12; Ishikawa 3H12; Ishikawa 3 H 12; Ishikawa3-H-12; Ishikawa clone 3-H-12; Ishikawa-H-12
Accession CVCL_D199
Resource Identification Initiative To cite this cell line use: Ishikawa 3-H-12 (RRID:CVCL_D199)
Comments Population: Japanese.
Doubling time: 24.0 hours (PubMed=9183638).
Derived from sampling site: Endometrium.
Sequence variations
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2529 (Ishikawa)
Children:
CVCL_7260 (ECC-1 )CVCL_C3G7 (Ishikawa 3-H-12 PRA-14 )CVCL_C3G8 (Ishikawa 3-H-12 PRB-59 )
CVCL_JG52 (Ishikawa 3-H-12-Luc )
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,11
D7S8209,10
D13S3179,12,13
D16S5399
TH019,10
TPOX8
vWA14,17

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Publications

PubMed=9183638
Nishida M., Kasahara K., Oki A., Satoh T., Arai Y., Kubo T.
Establishment of eighteen clones of Ishikawa cells.
Hum. Cell 9:109-116(1996)

DOI=10.1007/978-4-431-53981-0_2
Nishida M.
Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma.
(In) Cell and molecular biology of endometrial carcinoma; Kuramoto H., Nishida M. (eds.); pp.35-58; Springer; Tokyo (2003)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Cross-references
Cell line collections JCRB; JCRB1505
Cell line databases/resources CLO; CLO_0037230
Encyclopedic resources Wikidata; Q54898297
Polymorphism and mutation databases Cosmic; 871553
Cosmic; 889119
Cosmic; 1007163
Cosmic; 1066223
Cosmic; 1223489
Entry history
Entry creation22-Oct-2012
Last entry update16-Dec-2021
Version number14