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Cellosaurus SNU-449/Cas9-hyg (CVCL_C9G7)

[Text version]
Cell line name SNU-449/Cas9-hyg
Accession CVCL_C9G7
Resource Identification Initiative To cite this cell line use: SNU-449/Cas9-hyg (RRID:CVCL_C9G7)
Comments Population: Korean.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL530).
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11110; ARID1A; Simple; p.Glu2250Argfs*28 (c.6747dupA); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 903; AXIN1; Simple; p.Arg712Ter (c.2134C>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Arg (c.416A>G); ClinVar=VCV001500748; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0454 (SNU-449)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL530
Encyclopedic resources Wikidata; Q123033543
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2