ID   SNU-449/Cas9-hyg
AC   CVCL_C9G7
DR   GeneCopoeia; SL530
DR   Wikidata; Q123033543
CC   Population: Korean.
CC   Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL530).
CC   Sequence variation: Mutation; HGNC; 11110; ARID1A; Simple; p.Glu2250Argfs*28 (c.6747dupA); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 903; AXIN1; Simple; p.Arg712Ter (c.2134C>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys139Arg (c.416A>G); ClinVar=VCV001500748; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0454 ! SNU-449
SX   Male
AG   52Y
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-09-24; Version: 3
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