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Cellosaurus K1735-SW1 (CVCL_C8S5)

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Cell line name K1735-SW1
Synonyms K-1735 SW-1; K1735-SW-1; SW-1; SW1
Accession CVCL_C8S5
Resource Identification Initiative To cite this cell line use: K1735-SW1 (RRID:CVCL_C8S5)
Comments Characteristics: Highly metastatic. Established from a nonpigmented spontaneous lung metastasis produced by the parent tumor-growing subcutaneously (PubMed=3370643).
Transformant: NCIt; C17231; Ultraviolet radiation.
Miscellaneous: Direct author submission of STR profile from Fakhardo A.; STR performed by Labcorp Cell Line Testing.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_F828 (K1735)
Children:
CVCL_C8SM (SW1-C-CD83)CVCL_C8SL (SW1-P2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
Mouse STR 1-110
Mouse STR 1-216
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-515
Mouse STR 6-418
Mouse STR 6-712
Mouse STR 7-126
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-326.3
Mouse STR 17-216
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-127

Run an STR similarity search on this cell line
Publications

PubMed=3370643
Gabriele Schackert, Isaiah Joshua Fidler;
Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or meninges of syngeneic animals.
Cancer Res. 48:3478-3484(1988)

PubMed=2297053; PMCID=PMC1877453
Gabriele Schackert, Janet E. Price, Ruo-Dan Zhang, Corazon D. Bucana, Kyogo Itoh, Isaiah Joshua Fidler;
Regional growth of different human melanomas as metastases in the brain of nude mice.
Am. J. Pathol. 136:95-102(1990)

PubMed=12208865; DOI=10.1172/JCI16081; PMCID=PMC151112
Anindita Bhoumik, Tian-Gui Huang, Vladimir N. Ivanov, Lisa Gangi, Rui F. Qiao, Savio L.C. Woo, Shu-Hsia Chen, Ze'ev A. Ronai;
An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis.
J. Clin. Invest. 110:643-650(2002)

Cross-references
Encyclopedic resources Wikidata; Q123032785
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number5