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Cellosaurus SW1-P2 (CVCL_C8SL)

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Cell line name SW1-P2
Synonyms SW1-ATF2(50-100)
Accession CVCL_C8SL
Resource Identification Initiative To cite this cell line use: SW1-P2 (RRID:CVCL_C8SL)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:784; ATF2 (Note=With p.Met1_His49del and p.Glu101_Ser505del and a N-terminal HA tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCIt; C17231; Ultraviolet radiation.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_C8S5 (K1735-SW1)
Children:
CVCL_C8SN (SW1-P2-CD83)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=12208865; DOI=10.1172/JCI16081; PMCID=PMC151112
Anindita Bhoumik, Tian-Gui Huang, Vladimir N. Ivanov, Lisa Gangi, Rui F. Qiao, Savio L.C. Woo, Shu-Hsia Chen, Ze'ev A. Ronai;
An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis.
J. Clin. Invest. 110:643-650(2002)

PubMed=15051893; DOI=10.1073/pnas.0400880101; PMCID=PMC387361
Shi-Lin Yang, Yi Yang, John Raycraft, Hong-Tao Zhang, Sandra Kanan, Ya-Jun Guo, Ze'ev A. Ronai, Ingegerd Hellstrom, Karl Erik Hellstrom;
Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137.
Proc. Natl. Acad. Sci. U.S.A. 101:4990-4995(2004)

Cross-references
Encyclopedic resources Wikidata; Q123033578
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6