ID   K1735-SW1
AC   CVCL_C8S5
SY   K-1735 SW-1; K1735-SW-1; SW-1; SW1
DR   Wikidata; Q123032785
RX   PubMed=2297053;
RX   PubMed=3370643;
RX   PubMed=12208865;
CC   Characteristics: Highly metastatic. Established from a nonpigmented spontaneous lung metastasis produced by the parent tumor-growing subcutaneously (PubMed=3370643).
CC   Sequence variation: Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Miscellaneous: Direct author submission of STR profile from Fakhardo A.; STR performed by Labcorp Cell Line Testing.
CC   Breed/subspecies: C3H/HeN.
ST   Source(s): Direct_author_submission
ST   Mouse STR 1-1: 10
ST   Mouse STR 1-2: 16
ST   Mouse STR 2-1: 9
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 15
ST   Mouse STR 6-4: 18
ST   Mouse STR 6-7: 12
ST   Mouse STR 7-1: 26
ST   Mouse STR 8-1: 16
ST   Mouse STR 11-2: 16
ST   Mouse STR 12-1: 16
ST   Mouse STR 13-1: 17
ST   Mouse STR 15-3: 26.3
ST   Mouse STR 17-2: 16
ST   Mouse STR 18-3: 16
ST   Mouse STR 19-2: 12
ST   Mouse STR X-1: 27
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F828 ! K1735
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 4
//
RX   PubMed=2297053; PMCID=PMC1877453;
RA   Schackert G., Price J.E., Zhang R.-D., Bucana C.D., Itoh K.,
RA   Fidler I.J.;
RT   "Regional growth of different human melanomas as metastases in the
RT   brain of nude mice.";
RL   Am. J. Pathol. 136:95-102(1990).
//
RX   PubMed=3370643;
RA   Schackert G., Fidler I.J.;
RT   "Site-specific metastasis of mouse melanomas and a fibrosarcoma in the
RT   brain or meninges of syngeneic animals.";
RL   Cancer Res. 48:3478-3484(1988).
//
RX   PubMed=12208865; DOI=10.1172/JCI16081; PMCID=PMC151112;
RA   Bhoumik A., Huang T.-G., Ivanov V.N., Gangi L., Qiao R.F., Woo S.L.C.,
RA   Chen S.-H., Ronai Z.A.;
RT   "An ATF2-derived peptide sensitizes melanomas to apoptosis and
RT   inhibits their growth and metastasis.";
RL   J. Clin. Invest. 110:643-650(2002).
//