Cellosaurus Wnt-LIGHT (CVCL_C8QV)
| Cell line name | Wnt-LIGHT |
|---|---|
| Synonyms | WNT-LIGHT |
| Accession | CVCL_C8QV |
| Resource Identification Initiative | To cite this cell line use: Wnt-LIGHT (RRID:CVCL_C8QV) |
| Comments | Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=32268014). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384. Cell type: Fibroblast; CL=CL_0000057. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An. |
| Hierarchy | Parent: CVCL_0462 (NCTC clone 929) |
| Sex of cell | Male |
| Age at sampling | 100D |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=32268014; DOI=10.1002/cmdc.202000169; PMCID=PMC7311267 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q123033927 |
| Entry history | |
| Entry creation | 05-Oct-2023 |
| Last entry update | 14-Aug-2025 |
| Version number | 4 |