ID   Wnt-LIGHT
AC   CVCL_C8QV
SY   WNT-LIGHT
DR   Wikidata; Q123033927
RX   PubMed=32268014;
CC   Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=32268014).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C3H/An.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0462 ! NCTC clone 929
SX   Male
AG   100D
CA   Spontaneously immortalized cell line
DT   Created: 05-10-23; Last updated: 10-09-24; Version: 3
//
RX   PubMed=32268014; DOI=10.1002/cmdc.202000169; PMCID=PMC7311267;
RA   Hom M.E., Ondrus A.E., Sakata-Kato T., Rack P.G., Chen J.K.;
RT   "Bicyclic imidazolium inhibitors of Gli transcription factor
RT   activity.";
RL   ChemMedChem 15:1044-1049(2020).
//