Cellosaurus cell line HuH7-2C8 (CVCL

Cellosaurus HuH7-2C8 (CVCL_C8HQ)

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Cell line name

HuH7-2C8

Accession

CVCL_C8HQ

Resource Identification Initiative

To cite this cell line use: HuH7-2C8 (RRID:CVCL_C8HQ)

Comments

Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03138; Hepatitis B virus genotype D subtype ayw envelope protein (HBsAg).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).

Disease

Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0336 (Huh-7)
Children:

CVCL_C8HR (HuH7-2C8D)

Sex of cell

Male

Age at sampling

57Y