Cellosaurus logo
expasy logo

Cellosaurus HuH7-2C8 (CVCL_C8HQ)

[Text version]
Cell line name HuH7-2C8
Accession CVCL_C8HQ
Resource Identification Initiative To cite this cell line use: HuH7-2C8 (RRID:CVCL_C8HQ)
Comments Population: Japanese.
Transfected with: UniProtKB; P03138; Hepatitis B virus genotype D subtype ayw envelope protein (HBsAg).
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0336 (Huh-7)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line

PubMed=36511319; DOI=10.1016/j.antiviral.2022.105477
Bach C., Lucifora J., Delphin M., Heydmann L., Heuschkel M.J., Pons C., Goto K., Scheers E., Schuster C., Durantel D., Pauwels F., Baumert T.F., Verrier E.R.
A stable hepatitis D virus-producing cell line for host target and drug discovery.
Antiviral Res. 209:105477.1-105477.12(2023)

Encyclopedic resources Wikidata; Q123032649
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2