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Cellosaurus HEKExpress (CVCL_C8CE)

[Text version]
Cell line name HEKExpress
Accession CVCL_C8CE
Resource Identification Initiative To cite this cell line use: HEKExpress (RRID:CVCL_C8CE)
Comments Group: Serum/protein free medium cell line.
Characteristics: Grows in suspension growth conditions in animal component-free media.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Caution: This cell line is incorrectly described as being derived from HEK293 (instead of HEK293T) in PubMed=30591923.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Children:
CVCL_F0B4 (HEK2Express)CVCL_C8CF (HEKzeroT)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages Provider; ExcellGene; -; https://excellgene.com/technologies/hek293
Publications

PubMed=30591923; DOI=10.1016/j.omtm.2018.11.004; PMCID=PMC6305802
Daniel Blessing, Gabriel Vachey, Catherine Pythoud, Maria Rey, Vivianne Padrun, Florian Maria Wurm, Bernard L. Schneider, Nicole Deglon;
Scalable production of AAV vectors in orbitally shaken HEK293 cells.
Mol. Ther. Methods Clin. Dev. 13:14-26(2019)

PubMed=37232541; DOI=10.1002/bit.28414
Coralie Croissant, Joshua Armitano, Bertrand Lazuech, Danijel Svec, Cyril Pugin, Anais Guesdon, Louise Bryan, Antonio Castro, Lea Neuhaus, Giulia Fonti, Jacopo Martinis ...Show all 14 authors... , Maria Joao Wurm, Florian Maria Wurm, Paco Pino; Show fewer authors
A new T-antigen negative HEK293 cell line with improved AAV productivity.
Biotechnol. Bioeng. 120:1953-1960(2023)

Cross-references
Encyclopedic resources Wikidata; Q123031596
Entry history
Entry creation29-Jun-2023
Last entry update14-Aug-2025
Version number6