ID   HEKExpress
AC   CVCL_C8CE
DR   Wikidata; Q123031596
RX   PubMed=30591923;
RX   PubMed=37232541;
WW   https://excellgene.com/technologies/
CC   Group: Serum/protein free medium cell line.
CC   Characteristics: Grows in suspension growth conditions in animal component-free media.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
CC   Caution: This cell line is incorrectly described as being derived from HEK293 (instead of HERK293T) in PubMed=30591923.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0063 ! HEK293T
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 29-06-23; Last updated: 30-01-24; Version: 3
//
RX   PubMed=30591923; DOI=10.1016/j.omtm.2018.11.004;
RA   Blessing D., Vachey G., Pythoud C., Rey M., Padrun V., Wurm F.M.,
RA   Schneider B.L., Deglon N.;
RT   "Scalable production of AAV vectors in orbitally shaken HEK293
RT   cells.";
RL   Mol. Ther. Methods Clin. Dev. 13:14-26(2019).
//
RX   PubMed=37232541; DOI=10.1002/bit.28414;
RA   Croissant C., Armitano J., Lazuech B., Svec D., Pugin C., Guesdon A.,
RA   Bryan L., Castro A., Neuhaus L., Fonti G., Martinis J., Wurm M.J.,
RA   Wurm F.M., Pino P.;
RT   "A new T-antigen negative HEK293 cell line with improved AAV
RT   productivity.";
RL   Biotechnol. Bioeng. 120:1953-1960(2023).
//