Cellosaurus Dbt-MYCN/indP3F (CVCL_C7HL)
| Cell line name | Dbt-MYCN/indP3F |
|---|---|
| Accession | CVCL_C7HL |
| Resource Identification Initiative | To cite this cell line use: Dbt-MYCN/indP3F (RRID:CVCL_C7HL) |
| Comments | Characteristics: Transduced with a retroviral construct expressing MYCN constitutively and a doxycycline-inducible PAX3-FOXO1 lentiviral expression construct (PubMed=28138962). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3819; FOXO1 (Note=PAX3-FOXO1 fusion). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7559; MYCN. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8617; PAX3 (Note=PAX3-FOXO1 fusion). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134. Cell type: Muscle satellite cell; CL=CL_0000594. |
| Disease | Duchenne muscular dystrophy (NCIt: C75482) Duchenne muscular dystrophy (ORDO: Orphanet_98896) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C7HJ (Dbt) |
| Sex of cell | Male |
| Age at sampling | 7Y |
| Category | Telomerase immortalized cell line |
| Publications | PubMed=28138962; DOI=10.1002/path.4867; PMCID=PMC5357165 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q117704283 |
| Entry history | |
| Entry creation | 21-Mar-2023 |
| Last entry update | 10-Apr-2025 |
| Version number | 6 |