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Cellosaurus Dbt (CVCL_C7HJ)

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Cell line name Dbt
Accession CVCL_C7HJ
Resource Identification Initiative To cite this cell line use: Dbt (RRID:CVCL_C7HJ)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
Miscellaneous: Sex of donor and species used for Bmi1 transfection from personal communication of Cudre-Mauroux, Christophe.
Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
Cell type: Muscle satellite cell; CL=CL_0000594.
Disease Duchenne muscular dystrophy (NCIt: C75482)
Duchenne muscular dystrophy (ORDO: Orphanet_98896)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C7HK (Dbt-indP3F)CVCL_C7HL (Dbt-MYCN/indP3F)
Sex of cell Male
Age at sampling 7Y
Category Telomerase immortalized cell line
Publications

PubMed=14577914; DOI=10.1089/104303403322495034
Christophe Cudre-Mauroux, Teresa Occhiodoro, Stephane Konig, Patrick Salmon, Laurent Bernheim, Didier Trono;
Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a Duchenne myoblast cell line with long-term genotypic and phenotypic stability.
Hum. Gene Ther. 14:1525-1533(2003)

PubMed=19893043; DOI=10.2353/ajpath.2009.090192; PMCID=PMC2789624
Shu-Juan J. Xia, Dara D. Holder, Bruce R. Pawel, Chu-Ne Zhang, Frederic G. Barr;
High expression of the PAX3-FKHR oncoprotein is required to promote tumorigenesis of human myoblasts.
Am. J. Pathol. 175:2600-2608(2009)

Cross-references
Encyclopedic resources Wikidata; Q117704281
Entry history
Entry creation21-Mar-2023
Last entry update19-Dec-2024
Version number4