Cell line name |
HT29-16E |
Synonyms |
HT29 16E; HT-29 16E; HT29-Cl.16E; HT29-cl16E; HT29 clone 16E; Cl.16E |
Accession |
CVCL_C763 |
Resource Identification Initiative |
To cite this cell line use: HT29-16E (RRID:CVCL_C763) |
Comments |
Population: Caucasian. Doubling time: 43.37 hours (PubMed=25944804). Misspelling: C1.16E; Note=Occasionally. Misspelling: HT29-C1.16E; ABM=T8213; Note=In old versions, corrected in Jan 2025. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0320 (HT-29) |
Sex of cell |
Female |
Age at sampling |
44Y |
Category |
Cancer cell line |
Publications | PubMed=6744312 Chantal Augeron, Christian L. Laboisse; Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res. 44:3961-3969(1984) PubMed=8801204; DOI=10.1136/gut.38.2.240; PMCID=PMC1383030 Anne Jarry, Genevieve Vallette, Jean-Eric Branka, Christian L. Laboisse; Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-Cl.16E). Gut 38:240-242(1996) PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457 Sarah Bazzocco, Higinio Dopeso, Fernando Carton-Garcia, Irati Macaya, Elena Andretta, Fiona Chionh, Paulo Rodrigues, Miriam Garrido, Hafid Alazzouzi, Rocio Nieto, Alex Sanchez ...Show all 15 authors... , Simo Schwartz Jr., Josipa Bilic, John M. Mariadason, Diego Arango; Show fewer authors Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment. Clin. Cancer Res. 21:3695-3704(2015) |
Cross-references |
Cell line collections (Providers) |
ABM; T8213
|
Cell line databases/resources |
cancercelllines; CVCL_C763
|
Encyclopedic resources |
Wikidata; Q54896586
|
Entry history |
Entry creation | 22-Oct-2012 |
Last entry update | 10-Apr-2025 |
Version number | 24 |
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