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Cellosaurus 196hT (CVCL_C6VV)

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Cell line name 196hT
Synonyms hTERT-hMSCs
Accession CVCL_C6VV
Resource Identification Initiative To cite this cell line use: 196hT (RRID:CVCL_C6VV)
Comments Characteristics: Transduced with a lentiviral vector containing hTERT and eGFP respectively under the control of the CMV and EF1a promoters (PubMed=24561906).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6VW (MSOD)
Sex of cell Female
Age at sampling 51Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=24561906

Markers:
AmelogeninX
CSF1PO10,11
D3S135816,17
D5S81811,12
D7S82012
D8S117913,15
D13S31712,14
D16S53912
D18S5112,17
D21S1130,32.2
FGA21,23
Penta D11,13
Penta E10,14
TH019.3
TPOX8
vWA15,16

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Publications

Patent=WO2013186264A1
Paul-Emile Bourgine;
Immortalized mesenchymal stem cells that can be killed through an inducible apoptosis system.
Patent number WO2013186264A1, 19-Dec-2013

PubMed=24561906; DOI=10.1016/j.scr.2013.12.006
Paul-Emile Bourgine, Clementine Le Magnen, Sebastien Pigeot, Jeroen Geurts, Arnaud Scherberich, Ivan Martin;
Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survival.
Stem Cell Res. 12:584-598(2014)

Cross-references
Encyclopedic resources Wikidata; Q123030227
Entry history
Entry creation21-Mar-2023
Last entry update10-Apr-2025
Version number6