ID   196hT
AC   CVCL_C6VV
SY   hTERT-hMSCs
DR   Wikidata; Q123030227
RX   Patent=WO2013186264A1;
RX   PubMed=24561906;
CC   Characteristics: Transduced with a lentiviral vector containing hTERT and eGFP respectively under the control of the CMV and EF1a promoters (PubMed=24561906).
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
ST   Source(s): PubMed=24561906
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 12,14
ST   D16S539: 12
ST   D18S51: 12,17
ST   D21S11: 30,32.2
ST   D3S1358: 16,17
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 13,15
ST   FGA: 21,23
ST   Penta D: 11,13
ST   Penta E: 10,14
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 15,16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   51Y
CA   Telomerase immortalized cell line
DT   Created: 21-03-23; Last updated: 30-01-24; Version: 3
//
RX   Patent=WO2013186264A1;
RA   Bourgine P.-E.;
RT   "Immortalized mesenchymal stem cells that can be killed through an
RT   inducible apoptosis system.";
RL   Patent number WO2013186264A1, 19-Dec-2013.
//
RX   PubMed=24561906; DOI=10.1016/j.scr.2013.12.006;
RA   Bourgine P.-E., Le Magnen C., Pigeot S., Geurts J., Scherberich A.,
RA   Martin I.;
RT   "Combination of immortalization and inducible death strategies to
RT   generate a human mesenchymal stromal cell line with controlled
RT   survival.";
RL   Stem Cell Res. 12:584-598(2014).
//