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Cellosaurus EMRK1184luc (CVCL_C5RX)

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Cell line name EMRK1184luc
Accession CVCL_C5RX
Resource Identification Initiative To cite this cell line use: EMRK1184luc (RRID:CVCL_C5RX)
Comments Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Transformant: Myc.
Omics: Transcriptomics; RNAseq.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_C5RW (EMRK1184)
Category Cancer cell line
Publications

PubMed=30069049; DOI=10.1038/s41586-018-0387-5
Jonathan Bayldon Baell, David J. Leaver, Stefan J. Hermans, Gemma L. Kelly, Margs S. Brennan, Natalie L. Downer, Nghi Nguyen, Johannes Wichmann, Helen M. McRae, Yu-Qing Yang, Ben Cleary ...Show all 52 authors... , Helen Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah K. Vanyai, Maria I. Bergamasco, Rose E. May, Bethany K. Davey, Kimberly J. Morgan, Andrew J. Sealey, Beinan Wang, Natasha Zamudio, Stephen Wilcox, Alexandra L. Garnham, Bilal N. Sheikh, Brandon J. Aubrey, Karen Doggett, Matthew C. Chung, Melanie de Silva, John Bentley, Patricia A. Pilling, Meghan Hattarki, Olan Dolezal, Matthew L. Dennis, Hendrik Falk, Bin Ren, Susan A. Charman, Karen L. White, Jai Rautela, Andrea Newbold, Edwin D. Hawkins, Ricky W. Johnstone, Nicholas D. Huntington, Thomas S. Peat, Joan K. Heath, Andreas Strasser, Michael W. Parker, Gordon Keith Smyth, Ian P. Street, Brendon J. Monahan, Anne Kathrin Voss, Tim Thomas; Show fewer authors
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature 560:253-257(2018)

Cross-references
Encyclopedic resources Wikidata; Q116048933
Gene expression databases GEO; GSE114962
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number5