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Cellosaurus EMRK1184luc (CVCL_C5RX)

[Text version]
Cell line name EMRK1184luc
Accession CVCL_C5RX
Resource Identification Initiative To cite this cell line use: EMRK1184luc (RRID:CVCL_C5RX)
Comments Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Transformant: Myc.
Omics: Transcriptomics; RNAseq.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_C5RW (EMRK1184)
Category Cancer cell line
Publications

PubMed=30069049; DOI=10.1038/s41586-018-0387-5
Baell J.B., Leaver D.J., Hermans S.J., Kelly G.L., Brennan M.S., Downer N.L., Nguyen N., Wichmann J., McRae H.M., Yang Y.-Q., Cleary B., Lagiakos H.R., Mieruszynski S., Pacini G., Vanyai H.K., Bergamasco M.I., May R.E., Davey B.K., Morgan K.J., Sealey A.J., Wang B., Zamudio N., Wilcox S., Garnham A.L., Sheikh B.N., Aubrey B.J., Doggett K., Chung M.C., de Silva M., Bentley J., Pilling P.A., Hattarki M., Dolezal O., Dennis M.L., Falk H., Ren B., Charman S.A., White K.L., Rautela J., Newbold A., Hawkins E.D., Johnstone R.W., Huntington N.D., Peat T.S., Heath J.K., Strasser A., Parker M.W., Smyth G.K., Street I.P., Monahan B.J., Voss A.K., Thomas T.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature 560:253-257(2018)

Cross-references
Encyclopedic resources Wikidata; Q116048933
Gene expression databases GEO; GSE114962
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number4