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Cellosaurus EMRK1184 (CVCL_C5RW)

[Text version]
Cell line name EMRK1184
Synonyms EMRK-1184
Accession CVCL_C5RW
Resource Identification Initiative To cite this cell line use: EMRK1184 (RRID:CVCL_C5RW)
Comments Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
Transformant: Myc.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Children:
CVCL_C5RX (EMRK1184luc)
Category Cancer cell line
Publications

PubMed=30069049; DOI=10.1038/s41586-018-0387-5
Jonathan B. Baell, David J. Leaver, Stefan J. Hermans, Gemma L. Kelly, Margs S. Brennan, Natalie L. Downer, Nghi Nguyen, Johannes Wichmann, Helen M. McRae, Yu-Qing Yang, Ben Cleary ...Show all 52 authors... , Helen Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah K. Vanyai, Maria I. Bergamasco, Rose E. May, Bethany K. Davey, Kimberly J. Morgan, Andrew J. Sealey, Beinan Wang, Natasha Zamudio, Stephen Wilcox, Alexandra L. Garnham, Bilal N. Sheikh, Brandon J. Aubrey, Karen Doggett, Matthew C. Chung, Melanie de Silva, John Bentley, Patricia A. Pilling, Meghan Hattarki, Olan Dolezal, Matthew L. Dennis, Hendrik Falk, Bin Ren, Susan A. Charman, Karen L. White, Jai Rautela, Andrea Newbold, Edwin D. Hawkins, Ricky W. Johnstone, Nicholas D. Huntington, Thomas S. Peat, Joan K. Heath, Andreas Strasser, Michael W. Parker, Gordon Keith Smyth, Ian P. Street, Brendon J. Monahan, Anne Kathrin Voss, Tim Thomas; Show fewer authors
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature 560:253-257(2018)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4569157
ChEMBL-Targets; CHEMBL4569158
Encyclopedic resources Wikidata; Q116048932
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2