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Cellosaurus EMRK1184 (CVCL_C5RW)

[Text version]
Cell line name EMRK1184
Synonyms EMRK-1184
Accession CVCL_C5RW
Resource Identification Initiative To cite this cell line use: EMRK1184 (RRID:CVCL_C5RW)
Comments Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
Transformant: Myc.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Children:
CVCL_C5RX (EMRK1184luc)
Category Cancer cell line
Publications

PubMed=30069049; DOI=10.1038/s41586-018-0387-5
Baell J.B., Leaver D.J., Hermans S.J., Kelly G.L., Brennan M.S., Downer N.L., Nguyen N., Wichmann J., McRae H.M., Yang Y.-Q., Cleary B., Lagiakos H.R., Mieruszynski S., Pacini G., Vanyai H.K., Bergamasco M.I., May R.E., Davey B.K., Morgan K.J., Sealey A.J., Wang B., Zamudio N., Wilcox S., Garnham A.L., Sheikh B.N., Aubrey B.J., Doggett K., Chung M.C., de Silva M., Bentley J., Pilling P.A., Hattarki M., Dolezal O., Dennis M.L., Falk H., Ren B., Charman S.A., White K.L., Rautela J., Newbold A., Hawkins E.D., Johnstone R.W., Huntington N.D., Peat T.S., Heath J.K., Strasser A., Parker M.W., Smyth G.K., Street I.P., Monahan B.J., Voss A.K., Thomas T.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature 560:253-257(2018)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4569157
ChEMBL-Targets; CHEMBL4569158
Encyclopedic resources Wikidata; Q116048932
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2