ID   EMRK1184
AC   CVCL_C5RW
SY   EMRK-1184
DR   ChEMBL-Cells; CHEMBL4569157
DR   ChEMBL-Targets; CHEMBL4569158
DR   Wikidata; Q116048932
RX   PubMed=30069049;
CC   Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
CC   Transformant: Myc.
DI   NCIt; C21602; Mouse lymphoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 21-03-23; Version: 2
//
RX   PubMed=30069049; DOI=10.1038/s41586-018-0387-5;
RA   Baell J.B., Leaver D.J., Hermans S.J., Kelly G.L., Brennan M.S.,
RA   Downer N.L., Nguyen N., Wichmann J., McRae H.M., Yang Y.-Q.,
RA   Cleary B., Lagiakos H.R., Mieruszynski S., Pacini G., Vanyai H.K.,
RA   Bergamasco M.I., May R.E., Davey B.K., Morgan K.J., Sealey A.J.,
RA   Wang B., Zamudio N., Wilcox S., Garnham A.L., Sheikh B.N.,
RA   Aubrey B.J., Doggett K., Chung M.C., de Silva M., Bentley J.,
RA   Pilling P.A., Hattarki M., Dolezal O., Dennis M.L., Falk H., Ren B.,
RA   Charman S.A., White K.L., Rautela J., Newbold A., Hawkins E.D.,
RA   Johnstone R.W., Huntington N.D., Peat T.S., Heath J.K., Strasser A.,
RA   Parker M.W., Smyth G.K., Street I.P., Monahan B.J., Voss A.K.,
RA   Thomas T.;
RT   "Inhibitors of histone acetyltransferases KAT6A/B induce senescence
RT   and arrest tumour growth.";
RL   Nature 560:253-257(2018).
//