ID   EMRK1184luc
AC   CVCL_C5RX
DR   GEO; GSE114962
DR   Wikidata; Q116048933
RX   PubMed=30069049;
CC   Characteristics: Established from a tumor resulting from the expression of Myc under the control of the IgH enhancer (PubMed=30069049).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Transformant: Myc.
CC   Omics: Transcriptomics; RNAseq.
DI   NCIt; C21602; Mouse lymphoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_C5RW ! EMRK1184
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 10-04-25; Version: 4
//
RX   PubMed=30069049; DOI=10.1038/s41586-018-0387-5;
RA   Baell J.B., Leaver D.J., Hermans S.J., Kelly G.L., Brennan M.S.,
RA   Downer N.L., Nguyen N., Wichmann J., McRae H.M., Yang Y.-Q.,
RA   Cleary B., Lagiakos H.R., Mieruszynski S., Pacini G., Vanyai H.K.,
RA   Bergamasco M.I., May R.E., Davey B.K., Morgan K.J., Sealey A.J.,
RA   Wang B., Zamudio N., Wilcox S., Garnham A.L., Sheikh B.N.,
RA   Aubrey B.J., Doggett K., Chung M.C., de Silva M., Bentley J.,
RA   Pilling P.A., Hattarki M., Dolezal O., Dennis M.L., Falk H., Ren B.,
RA   Charman S.A., White K.L., Rautela J., Newbold A., Hawkins E.D.,
RA   Johnstone R.W., Huntington N.D., Peat T.S., Heath J.K., Strasser A.,
RA   Parker M.W., Smyth G.K., Street I.P., Monahan B.J., Voss A.K.,
RA   Thomas T.;
RT   "Inhibitors of histone acetyltransferases KAT6A/B induce senescence
RT   and arrest tumour growth.";
RL   Nature 560:253-257(2018).
//