| Cell line name |
NW145/E7 |
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| Synonyms |
NW-145/E7; NW145 clone E7 |
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| Accession |
CVCL_C538 |
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| Resource Identification Initiative |
To cite this cell line use: NW145/E7 (RRID:CVCL_C538) |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
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| HLA typing |
Source: PubMed=15592718
| Class I | | HLA-A | A*23:01,23:01 | | HLA-B | B*15:01:01:01,15:01:01:01 | | HLA-C | C*01:02,01:02 | | Class II | | HLA-DP | DPB1*04:02,04:02 | | HLA-DQ | DQB1*03:01:01,03:01:01 | | HLA-DR | DRB1*11:01,11:01 |
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| Disease |
Cutaneous melanoma (NCIt: C3510) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_2148 (NW145) |
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| Sex of cell |
Male |
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| Age at sampling |
Age unspecified |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): ESTDAB=ESTDAB-058
Markers:
Run an STR similarity search on this cell line |
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| Publications | PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005) PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Rosa Mendez, Natalia Aptsiauri, Ana Del Campo, Isabel Maleno, Teresa Cabrera, Francisco Ruiz-Cabello Osuna, Federico Garrido, Angel Garcia-Lora;
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_C538
ESTDAB; ESTDAB-058
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| Encyclopedic resources |
Wikidata; Q54931192
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| Polymorphism and mutation databases |
Cosmic; 972259
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 14-Aug-2025 |
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| Version number | 14 |
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