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Cellosaurus NW145 (CVCL_2148)

[Text version]
Cell line name NW145
Synonyms NW-145; NW 145; NW-MEL-145; NW-Mel-145; EST57
Accession CVCL_2148
Resource Identification Initiative To cite this cell line use: NW145 (RRID:CVCL_2148)
Comments Omics: Variations; Array-based CGH.
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*23:01,23:01
HLA-BB*15:01:01:01,15:01:01:01
HLA-CC*01:02,01:02
Class II
HLA-DPDPB1*04:02
HLA-DQDQB1*06:04,03:01:01
HLA-DRDRB1*04:01,11:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C538 (NW145/E7)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-057

Markers:
AmelogeninX,Y
CSF1PO12
D3S135814,15
D5S81811
D7S82010
D13S31711,12
FGA20
TH017
TPOX11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Goran Jonsson, Christina Dahl, Johan Staaf, Troy Sandberg, Par-Ola Bendahl, Markus Ringner, Per Guldberg, Ake Borg;
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_2148
ESTDAB; ESTDAB-057
Encyclopedic resources Wikidata; Q54931191
Gene expression databases GEO; GSM156014
Polymorphism and mutation databases Cosmic; 972264
Cosmic; 1047648
Cosmic; 2163798
IARC_TP53; 26075
Progenetix; CVCL_2148
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number23