ID   NW145/E7
AC   CVCL_C538
SY   NW-145/E7; NW145 clone E7
DR   cancercelllines; CVCL_C538
DR   Cosmic; 972259
DR   ESTDAB; ESTDAB-058
DR   Wikidata; Q54931192
RX   PubMed=15592718;
RX   PubMed=19340423;
CC   HLA typing: A*23:01,23:01; B*15:01:01:01,15:01:01:01; C*01:02,01:02; DPB1*04:02,04:02; DQB1*03:01:01,03:01:01; DRB1*11:01,11:01 (PubMed=15592718).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
ST   Source(s): ESTDAB=ESTDAB-058
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 11,12
ST   D3S1358: 14,15
ST   D5S818: 11
ST   D7S820: 10
ST   FGA: 20
ST   TH01: 7
ST   TPOX: 11
ST   vWA: 19
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2148 ! NW145
SX   Male
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 13
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RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
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RX   PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131;
RA   Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T.,
RA   Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.;
RT   "HLA and melanoma: multiple alterations in HLA class I and II
RT   expression in human melanoma cell lines from ESTDAB cell bank.";
RL   Cancer Immunol. Immunother. 58:1507-1515(2009).
//