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Cellosaurus KB N10 (CVCL_C4YP)

[Text version]
Cell line name KB N10
Synonyms N10
Accession CVCL_C4YP
Resource Identification Initiative To cite this cell line use: KB N10 (RRID:CVCL_C4YP)
Comments Problematic cell line: Contaminated. Parent cell line (KB) has been shown to be a HeLa derivative.
Population: African American.
Characteristics: Radioresistant: 1.50 to 3.75-fold more resistant to X-irradiation than the parental cell line (PubMed=9659517).
Selected for resistance to: ChEBI; CHEBI:22907; Bleomycin.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0372 (KB)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=9439682; DOI=10.1111/j.1349-7006.1997.tb00331.x
Yanagisawa T., Urade M., Takahashi Y., Yamamoto Y., Furuyama J.-i.
Levels of superoxide dismutases, glutathione, and poly(ADP-ribose) polymerase in radioresistant human KB carcinoma cell line.
Jpn. J. Cancer Res. 88:1070-1077(1997)

PubMed=9659517; DOI=10.1016/S1368-8375(97)00048-1
Yanagisawa T., Urade M., Takahashi Y., Kishimoto H., Sakurai K.
Isolation and characterisation of radioresistant human KB carcinoma cells in vitro.
Oral Oncol. 34:30-38(1998)

PubMed=9930366; DOI=10.1016/S1368-8375(98)00045-1
Yanagisawa T., Urade M., Yamamoto Y., Furuyama J.-i.
Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10.
Oral Oncol. 34:524-528(1998)

Encyclopedic resources Wikidata; Q116049614
Entry history
Entry creation15-Dec-2022
Last entry update05-Oct-2023
Version number4