ID   KB N10
AC   CVCL_C4YP
SY   N10
DR   Wikidata; Q116049614
RX   PubMed=9439682;
RX   PubMed=9659517;
RX   PubMed=9930366;
CC   Problematic cell line: Contaminated. Parent cell line (KB) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Characteristics: Radioresistant: 1.50 to 3.75-fold more resistant to X-irradiation than the parental cell line (PubMed=9659517).
CC   Selected for resistance to: ChEBI; CHEBI:22907; Bleomycin.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0372 ! KB
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 05-10-23; Version: 4
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RX   PubMed=9439682; DOI=10.1111/j.1349-7006.1997.tb00331.x;
RA   Yanagisawa T., Urade M., Takahashi Y., Yamamoto Y., Furuyama J.-i.;
RT   "Levels of superoxide dismutases, glutathione, and poly(ADP-ribose)
RT   polymerase in radioresistant human KB carcinoma cell line.";
RL   Jpn. J. Cancer Res. 88:1070-1077(1997).
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RX   PubMed=9659517; DOI=10.1016/s1368-8375(97)00048-1;
RA   Yanagisawa T., Urade M., Takahashi Y., Kishimoto H., Sakurai K.;
RT   "Isolation and characterisation of radioresistant human KB carcinoma
RT   cells in vitro.";
RL   Oral Oncol. 34:30-38(1998).
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RX   PubMed=9930366; DOI=10.1016/s1368-8375(98)00045-1;
RA   Yanagisawa T., Urade M., Yamamoto Y., Furuyama J.-i.;
RT   "Increased expression of human DNA repair genes, XRCC1, XRCC3 and
RT   RAD51, in radioresistant human KB carcinoma cell line N10.";
RL   Oral Oncol. 34:524-528(1998).
//