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Cellosaurus WRL-LFBK-alphavbeta6 (CVCL_C4XX)

[Text version]
Cell line name WRL-LFBK-alphavbeta6
Synonyms WRL-LFBK-avb6
Accession CVCL_C4XX
Resource Identification Initiative To cite this cell line use: WRL-LFBK-alphavbeta6 (RRID:CVCL_C4XX)
Comments Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig.
Virology: Treatment of the parent cell line with the aromatic cationic compound DB772 has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34458357).
Transfected with: VGNC; 30323; Bovine ITGAV.
Transfected with: VGNC; 30331; Bovine ITGB6.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Hierarchy Parent: CVCL_RX27 (LFBK-alphaVbeta6)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Spontaneously immortalized cell line

PubMed=34458357; DOI=10.3389/fvets.2021.715120
Gray A.R., Wood B.A., Henry E., King D.P., Mioulet V.
Elimination of non-cytopathic bovine viral diarrhea virus from the LFBK-alphavbeta6 cell line.
Front. Vet. Sci. 8:715120.1-715120.5(2021)

Encyclopedic resources Wikidata; Q116050799
Entry history
Entry creation15-Dec-2022
Last entry update05-Oct-2023
Version number3