ID   WRL-LFBK-alphavbeta6
AC   CVCL_C4XX
SY   WRL-LFBK-avb6
DR   Wikidata; Q116050799
RX   PubMed=34458357;
CC   Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig.
CC   Virology: Treatment of the parent cell line with the aromatic cationic compound DB772 has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34458357).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=VGNC; VGNC:30323; Bovine ITGAV.
CC   Genetic integration: Method=Transduction; Gene=VGNC; VGNC:30331; Bovine ITGB6.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
HI   CVCL_RX27 ! LFBK-alphaVbeta6
SX   Sex unspecified
AG   Age unspecified
CA   Spontaneously immortalized cell line
DT   Created: 15-12-22; Last updated: 10-04-25; Version: 6
//
RX   PubMed=34458357; DOI=10.3389/fvets.2021.715120; PMCID=PMC8385193;
RA   Gray A.R., Wood B.A., Henry E., King D.P., Mioulet V.;
RT   "Elimination of non-cytopathic bovine viral diarrhea virus from the
RT   LFBK-alphavbeta6 cell line.";
RL   Front. Vet. Sci. 8:715120.1-715120.5(2021).
//