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Cellosaurus WM873-2 (CVCL_C285)

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Cell line name WM873-2
Synonyms WM-873-2; WM 873-2; WML-873-2
Accession CVCL_C285
Resource Identification Initiative To cite this cell line use: WM873-2 (RRID:CVCL_C285)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from autologous cell lines WM740V; WM858; WM873-1).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L030 ! WM740V
CVCL_C283 ! WM858
CVCL_C284 ! WM873-1
CVCL_C286 ! WM873-3
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133822,23
D3S135817
D5S81810,12
D7S8209,10
D8S117912,13
D13S31711
D16S5398
D18S5114
D19S43313,15
D21S1129,32.2
FGA20,23
TH016,8
TPOX8
vWA16,17

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Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Meenhard Herlyn, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, DuPont Guerry 4th, Ruth Halaban, Dorothee Herlyn, David E. Elder, Gerd G. Maul, Zenon Steplewski, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Meenhard Herlyn, Jan Thurin, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, Dorothee Herlyn, David E. Elder, Edward Bondi, DuPont Guerry 4th, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM873-2-01-0001
Cell line databases/resources cancercelllines; CVCL_C285
Encyclopedic resources Wikidata; Q54994331
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number22