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Cellosaurus WM858 (CVCL_C283)

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Cell line name WM858
Synonyms WM-858; WM 858; Wm858; WML-858
Accession CVCL_C283
Resource Identification Initiative To cite this cell line use: WM858 (RRID:CVCL_C283)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L030 ! WM740V
CVCL_C284 ! WM873-1
CVCL_C285 ! WM873-2
CVCL_C286 ! WM873-3
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133822,23
D3S135817
D5S81810,12
D7S8209,10
D8S117912,13
D13S31711
D16S5398,12
D18S5114
D19S43313,15
D21S1129,32.2
FGA20,23
TH016,8
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Meenhard Herlyn, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, DuPont Guerry 4th, Ruth Halaban, Dorothee Herlyn, David E. Elder, Gerd G. Maul, Zenon Steplewski, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Meenhard Herlyn, Jan Thurin, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, Dorothee Herlyn, David E. Elder, Edward Bondi, DuPont Guerry 4th, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM858-01-0001
Cell line databases/resources cancercelllines; CVCL_C283
Encyclopedic resources Wikidata; Q54994326
Gene expression databases GEO; GSM109045
GEO; GSM186497
GEO; GSM186498
GEO; GSM952588
Polymorphism and mutation databases Cosmic; 1155558
Progenetix; CVCL_C283
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number24