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Cellosaurus WM873-1 (CVCL_C284)

[Text version]
Cell line name WM873-1
Synonyms WM-873-1; WM 873-1; WML-873-1
Accession CVCL_C284
Resource Identification Initiative To cite this cell line use: WM873-1 (RRID:CVCL_C284)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L030 ! WM740V
CVCL_C283 ! WM858
CVCL_C285 ! WM873-2
CVCL_C286 ! WM873-3
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133822,23
D3S135817
D5S81810,12
D7S8209,10
D8S117912,13
D13S31711
D16S5398,12
D18S5114
D19S43313,15
D21S1129,32.2
FGA20,23
TH016,8
TPOX8
vWA16,17

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Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Herlyn M., Balaban-Malenbaum G.B., Bennicelli J.L., Guerry D. 4th, Halaban R., Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C., Clark W.H. Jr., Koprowski H.
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Herlyn M., Thurin J., Balaban-Malenbaum G.B., Bennicelli J.L., Herlyn D., Elder D.E., Bondi E., Guerry D. 4th, Nowell P.C., Clark W.H. Jr., Koprowski H.
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM873-1-01-0001
Cell line databases/resources cancercelllines; CVCL_C284
Encyclopedic resources Wikidata; Q54994329
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number20