Cellosaurus HB-2 (CVCL_C1LF)
| Cell line name | HB-2 |
|---|---|
| Synonyms | HB-second generation |
| Accession | CVCL_C1LF |
| Resource Identification Initiative | To cite this cell line use: HB-2 (RRID:CVCL_C1LF) |
| Comments | Characteristics: Increased tumorigenicity compared to the parent cell line. Established from a tumor obtained from inoculation of the parent cell line in nude mice (PubMed=20464641). Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Transformant: ChEBI; CHEBI_29865; Benzo[a]pyrene. Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729. Cell type: Epithelial cell; CL=CL_0000066. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_6E44 (HIOEC-B(a)P-96) |
| Sex of cell | Female |
| Age at sampling | Age unspecified |
| Category | Transformed cell line |
| Publications | PubMed=20464641; DOI=10.1007/s12032-010-9558-4 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q114311564 |
| Entry history | |
| Entry creation | 22-Sep-2022 |
| Last entry update | 14-Aug-2025 |
| Version number | 8 |