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Cellosaurus HIOEC-B(a)P-96 (CVCL_6E44)

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Cell line name HIOEC-B(a)P-96
Synonyms HB96
Accession CVCL_6E44
Resource Identification Initiative To cite this cell line use: HIOEC-B(a)P-96 (RRID:CVCL_6E44)
Comments Characteristics: Tumorigenic (PubMed=18206853).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: ChEBI; CHEBI_29865; Benzo[a]pyrene.
Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6E43 (HIOEC)
Children:
CVCL_C1LF (HB-2)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=18206853; DOI=10.1016/j.archoralbio.2007.12.002
Lai-Ping Zhong, Hong-Ya Pan, Xiao-Jian Zhou, Dong-Xia Ye, Lei Zhang, Xiao Yang, Wan-Tao Chen, Zhi-Yuan Zhang;
Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by benzo(a)pyrene from human immortalized oral epithelial cell line.
Arch. Oral Biol. 53:443-452(2008)

PubMed=20464641; DOI=10.1007/s12032-010-9558-4
Dong-Xia Ye, Xiao-Jian Zhou, Hong-Ya Pan, Qian Jiang, Lai-Ping Zhong, Wan-Tao Chen, Zhi-Yuan Zhang;
Establishment and characterization of an HPV16 E6/E7-expressing oral squamous cell carcinoma cell line with enhanced tumorigenicity.
Med. Oncol. 28:1331-1337(2011)

Cross-references
Encyclopedic resources Wikidata; Q54889588
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number14