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Cellosaurus RPTEC_MTAP_C6 (CVCL_C1CK)

[Text version]
Cell line name RPTEC_MTAP_C6
Accession CVCL_C1CK
Resource Identification Initiative To cite this cell line use: RPTEC_MTAP_C6 (RRID:CVCL_C1CK)
Comments Characteristics: Control cell line for the cancer pathway knockout panel.
Knockout cell: Method=CRISPR/Cas9; HGNC; 7413; MTAP.
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_K278 (RPTEC/TERT1)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line

PubMed=35692635; DOI=10.1016/j.isci.2022.104437
Cook A.L., Wyhs N., Sur S., Ptak B., Popoli M., Dobbyn L., Papadopoulos T., Bettegowda C., Papadopoulos N., Vogelstein B., Zhou S.-B., Kinzler K.W.
An isogenic cell line panel for sequence-based screening of targeted anticancer drugs.
IScience 25:104437.1-104437.14(2022)

Encyclopedic resources Wikidata; Q114312914
Entry history
Entry creation22-Sep-2022
Last entry update29-Jun-2023
Version number4