ID   RPTEC_MTAP_C6
AC   CVCL_C1CK
DR   Wikidata; Q114312914
RX   PubMed=35692635;
CC   Characteristics: Control cell line for the cancer pathway knockout panel.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7413; MTAP.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
CC   Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_K278 ! RPTEC/TERT1
SX   Male
AG   Adult
CA   Telomerase immortalized cell line
DT   Created: 22-09-22; Last updated: 14-08-25; Version: 7
//
RX   PubMed=35692635; DOI=10.1016/j.isci.2022.104437; PMCID=PMC9184558;
RA   Cook, Ashley L.
RA   Wyhs, Nicolas
RA   Sur, Surojit
RA   Ptak, Blair
RA   Popoli, Maria
RA   Dobbyn, Laura
RA   Papadopoulos, Tasos
RA   Bettegowda, Chetan
RA   Papadopoulos, Nickolas
RA   Vogelstein, Bert
RA   Zhou, Shi-Bin
RA   Kinzler, Kenneth Wayne
RT   "An isogenic cell line panel for sequence-based screening of targeted
RT   anticancer drugs.";
RL   iScience 25:104437.1-104437.13(2022).
//