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Cellosaurus HUDEP2 HBB-KO (CVCL_C0QM)

[Text version]
Cell line name HUDEP2 HBB-KO
Accession CVCL_C0QM
Resource Identification Initiative To cite this cell line use: HUDEP2 HBB-KO (RRID:CVCL_C0QM)
Comments Population: Japanese.
Knockout cell: Method=CRISPR/Cas9; HGNC; 4827; HBB.
Transfected with: UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Transfected with: UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Chromatin accessibility by ATAC-seq.
Omics: Deep quantitative proteome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: Erythroid progenitor cell; CL=CL_0000038.
Disease Sickle cell disease (NCIt: C34383)
Sickle cell anemia (ORDO: Orphanet_232)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VI06 (HUDEP-2)
Sex of cell Sex unspecified
Age at sampling <1D
Category Transformed cell line

PubMed=35269949; DOI=10.3390/ijms23052807
Zhou G.-Q., Zhang H.-K., Lin A.-N., Wu Z., Li T., Zhang X.-M., Chen H.-Y., Lu D.-R.
Multi-omics analysis in beta-thalassemia using an HBB gene-knockout human erythroid progenitor cell model.
Int. J. Mol. Sci. 23:2807.1-2807.14(2022)

Encyclopedic resources Wikidata; Q112929794
Proteomic databases PRIDE; PXD030182
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5