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Cellosaurus RUES2 (CVCL_B810)

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Cell line name RUES2
Synonyms Rockefeller University Embryonic Stem cell line 2; RUESe002-A
Accession CVCL_B810
Resource Identification Initiative To cite this cell line use: RUES2 (RRID:CVCL_B810)
Comments From: Rockefeller University; New York; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0013.
Registration: Swiss research registry; BAG-hES-IMP-0057.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VM28 (RUES2 HOPX KO)CVCL_VM29 (RUES2 HOPX-tdTomato)CVCL_WN79 (RUES2 SFTPC-tdTomato)
CVCL_IQ87 (RUES2-EGFP/SMAD7)CVCL_C1W2 (RUESe002-A-1)CVCL_C1W3 (RUESe002-A-2)
CVCL_C1W4 (RUESe002-A-4)CVCL_C1W5 (RUESe002-A-5)CVCL_E9CV (RUESe002-A-6)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): WiCell=rues2

Markers:
AmelogeninX
CSF1PO11
D3S135814,15
D5S81811,12
D7S82012,13
D8S117910,13
D13S31711
D16S53912,15
D18S5116,18
D21S1129
FGA22,25
Penta D9,12
Penta E13,14
TH017,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Web pages Provider; Rockefeller University; -; https://rues.rockefeller.edu/
Publications

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

PubMed=35805069; DOI=10.3390/cells11131984; PMCID=PMC9265327
Francisco Jose Molina-Ruiz, Clelia Introna, Georgina Bombau, Mireia Galofre, Josep Maria Canals;
Standardization of cell culture conditions and routine genomic screening under a quality management system leads to reduced genomic instability in hPSCs.
Cells 11:1984.1-1984.25(2022)

Cross-references
Cell line collections (Providers) WiCell; rues2
Cell line databases/resources hPSCreg; RUESe002-A
NIHhESC; NIHhESC-10-0013
Biological sample resources 4DN; 4DNSR2VQCV9W
BioSamples; SAMEA104387770
ENCODE; ENCBS089ZVW
Encyclopedic resources Wikidata; Q54951469
Experimental variables resources EFO; EFO_0009320
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24