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Cellosaurus Twin-N-iPSCs line#7 (CVCL_B4L3)

[Text version]
Cell line name Twin-N-iPSCs line#7
Synonyms Twin-N-iPSC; T2N iPS; 46XX-iPSC; Twin-D21-iPSCs line #7; UNIGEi004-A
Accession CVCL_B4L3
Resource Identification Initiative To cite this cell line use: Twin-N-iPSCs line#7 (RRID:CVCL_B4L3)
Comments From: University of Geneva; Geneva; Switzerland.
Population: Caucasian.
Karyotypic information: 46,XX (PubMed=32739879).
Omics: Transcriptome analysis by RNAseq.
Donor information: Twin-DS-iPSC (Cellosaurus=CVCL_W088) and Twin-N-iPSC originate from monozygotic twins discordant for trisomy 21.
Derived from site: In situ; Forearm, skin; UBERON=UBERON_0003399.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B4L2 (Twin-N)
Sex of cell Female
Age at sampling 16FW
Category Induced pluripotent stem cell
Publications

PubMed=24375627; DOI=10.1002/emmm.201302848
Hibaoui Y., Grad I., Letourneau A., Sailani M.R., Dahoun S., Santoni F.A., Gimelli S., Guipponi M., Pelte M.-F., Sloan-Bena F., Antonarakis S.E., Feki A.
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21.
EMBO Mol. Med. 6:259-277(2014)

PubMed=24740065; DOI=10.1038/nature13200
Letourneau A., Santoni F.A., Bonilla X., Sailani M.R., Gonzalez D., Kind J., Chevalier C., Thurman R., Sandstrom R.S., Hibaoui Y., Garieri M., Popadin K.Y., Falconnet E., Gagnebin M., Gehrig C., Vannier A., Guipponi M., Farinelli L., Robyr D., Migliavacca E., Borel C., Deutsch S., Feki A., Stamatoyannopoulos J.A., Herault Y., van Steensel B., Guigo R., Antonarakis S.E.
Domains of genome-wide gene expression dysregulation in Down's syndrome.
Nature 508:345-350(2014)

PubMed=32739879; DOI=10.1016/j.scr.2020.101920
Feki A., Sloan-Bena F., Hibaoui Y.
Parallel derivation of X-monosomy induced pluripotent stem cells (iPSCs) with isogenic control iPSCs.
Stem Cell Res. 47:101920-101920(2020)

Cross-references
Cell line databases/resources hPSCreg; UNIGEi004-A
Encyclopedic resources Wikidata; Q110433295
Gene expression databases GEO; GSM1338322
Entry history
Entry creation16-Dec-2021
Last entry update29-Jun-2023
Version number6