ID   Twin-N-iPSCs line#7
AC   CVCL_B4L3
SY   Twin-N-iPSC; T2N iPS; 46XX-iPSC; Twin-D21-iPSCs line #7; UNIGEi004-A
DR   GEO; GSM1338322
DR   hPSCreg; UNIGEi004-A
DR   Wikidata; Q110433295
RX   PubMed=24375627;
RX   PubMed=24740065;
RX   PubMed=32739879;
CC   From: University of Geneva; Geneva; Switzerland.
CC   Population: Caucasian.
CC   Karyotypic information: 46,XX (PubMed=32739879).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Donor information: Twin-DS-iPSC (Cellosaurus=CVCL_W088) and Twin-N-iPSC originate from monozygotic twins discordant for trisomy 21.
CC   Derived from site: In situ; Forearm, skin; UBERON=UBERON_0003399.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B4L2 ! Twin-N
SX   Female
AG   16FW
CA   Induced pluripotent stem cell
DT   Created: 16-12-21; Last updated: 29-06-23; Version: 6
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RX   PubMed=24375627; DOI=10.1002/emmm.201302848;
RA   Hibaoui Y., Grad I., Letourneau A., Sailani M.R., Dahoun S.,
RA   Santoni F.A., Gimelli S., Guipponi M., Pelte M.-F., Sloan-Bena F.,
RA   Antonarakis S.E., Feki A.;
RT   "Modelling and rescuing neurodevelopmental defect of Down syndrome
RT   using induced pluripotent stem cells from monozygotic twins discordant
RT   for trisomy 21.";
RL   EMBO Mol. Med. 6:259-277(2014).
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RX   PubMed=24740065; DOI=10.1038/nature13200;
RA   Letourneau A., Santoni F.A., Bonilla X., Sailani M.R., Gonzalez D.,
RA   Kind J., Chevalier C., Thurman R., Sandstrom R.S., Hibaoui Y.,
RA   Garieri M., Popadin K.Y., Falconnet E., Gagnebin M., Gehrig C.,
RA   Vannier A., Guipponi M., Farinelli L., Robyr D., Migliavacca E.,
RA   Borel C., Deutsch S., Feki A., Stamatoyannopoulos J.A., Herault Y.,
RA   van Steensel B., Guigo R., Antonarakis S.E.;
RT   "Domains of genome-wide gene expression dysregulation in Down's
RT   syndrome.";
RL   Nature 508:345-350(2014).
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RX   PubMed=32739879; DOI=10.1016/j.scr.2020.101920;
RA   Feki A., Sloan-Bena F., Hibaoui Y.;
RT   "Parallel derivation of X-monosomy induced pluripotent stem cells
RT   (iPSCs) with isogenic control iPSCs.";
RL   Stem Cell Res. 47:101920-101920(2020).
//