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Cellosaurus KBM-7 P1-55 (CVCL_B253)

[Text version]

Cell line name KBM-7 P1-55
Synonyms P1-55
Accession CVCL_B253
Resource Identification Initiative To cite this cell line use: KBM-7 P1-55 (RRID:CVCL_B253)
Comments Group: Haploid karyotype cell line.
Karyotypic information: Haploid except for a disomy of chromosome 8.
Derived from sampling site: Bone marrow.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A426 (KBM-7)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=10527618; DOI=10.1006/excr.1999.4656
Kotecki M., Reddy P.S., Cochran B.H.
Isolation and characterization of a near-haploid human cell line.
Exp. Cell Res. 252:273-280(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Encyclopedic resources Wikidata; Q54899586
Entry history
Entry creation06-Jun-2012
Last entry update23-Sep-2021
Version number16