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Cellosaurus 293.STAT1 BAX KO (CVCL_B0NB)

[Text version]
Cell line name 293.STAT1 BAX KO
Accession CVCL_B0NB
Resource Identification Initiative To cite this cell line use: 293.STAT1 BAX KO (RRID:CVCL_B0NB)
Comments Characteristics: Exhibits significantly increased adeno-associated virus (AAV) production capacity for gene therapy applications (ATCC=CRL-1573-VHG).
Knockout cell: Method=CRISPR/Cas9; HGNC; 959; BAX.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11362; STAT1.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

CLPUB00659
Turner-Gillies E., Shapiro B.A., Tian F.
Generation of cell lines capable of producing high-titer viral stocks for use in vaccine manufacture and gene therapy.
(In) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas (2021)

Cross-references
Cell line collections (Providers) ATCC; CRL-1573-VHG
Encyclopedic resources Wikidata; Q108819497
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4