ID   293.STAT1 BAX KO
AC   CVCL_B0NB
DR   ATCC; CRL-1573-VHG
DR   Wikidata; Q108819497
RX   CelloPub=CLPUB00659;
CC   Characteristics: Exhibits significantly increased adeno-associated virus (AAV) production capacity for gene therapy applications (ATCC=CRL-1573-VHG).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:959; BAX.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11362; STAT1.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 5
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RX   CelloPub=CLPUB00659;
RA   Turner-Gillies E., Shapiro B.A., Tian F.;
RT   "Generation of cell lines capable of producing high-titer viral stocks
RT   for use in vaccine manufacture and gene therapy.";
RL   (In technical document) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas; USA (2021).
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