Cellosaurus logo
expasy logo

Cellosaurus PC3-epi (CVCL_B0CB)

[Text version]
Cell line name PC3-epi
Synonyms PC3-Epi
Accession CVCL_B0CB
Resource Identification Initiative To cite this cell line use: PC3-epi (RRID:CVCL_B0CB)
Comments Population: Caucasian.
Characteristics: Selected based on an epithelial cell morphology, bioluminescent intensity and expression of E-cadherin. Selection was repeated twice and a stable epithelial population was obtained (PubMed=24124593).
Characteristics: Transfected with a pLentilox-EV-Luc luciferase expression vector.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line

PubMed=24124593; DOI=10.1371/journal.pone.0076773
Roca H., Hernandez J.R., Weidner S., McEachin R.C., Fuller D., Sud S., Schumann T., Wilkinson J.E., Zaslavsky A., Li H.-W., Maher C.A., Daignault-Newton S., Healy P.N., Pienta K.J.
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer.
PLoS ONE 8:E76773-E76773(2013)

PubMed=25426557; DOI=10.18632/oncotarget.2766
Shiraishi T., Verdone J.E., Huang J., Kahlert U.D., Hernandez J.R., Torga G., Zarif J.C., Epstein T., Gatenby R., McCartney A., Elisseeff J.H., Mooney S.M., An S.S., Pienta K.J.
Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells.
Oncotarget 6:130-143(2015)

Cell line collections (Providers) ATCC; CRL-3470
Cell line databases/resources cancercelllines; CVCL_B0CB
Encyclopedic resources Wikidata; Q108821094
Gene expression databases GEO; GSM1063981
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number5