ID   PC3-epi
AC   CVCL_B0CB
SY   PC3-Epi
DR   ATCC; CRL-3470
DR   cancercelllines; CVCL_B0CB
DR   GEO; GSM1063981
DR   Wikidata; Q108821094
RX   PubMed=24124593;
RX   PubMed=25426557;
CC   Population: Caucasian.
CC   Characteristics: Selected based on an epithelial cell morphology, bioluminescent intensity and expression of E-cadherin. Selection was repeated twice and a stable epithelial population was obtained (PubMed=24124593).
CC   Characteristics: Transfected with a pLentilox-EV-Luc luciferase expression vector.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 05-10-23; Version: 5
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RX   PubMed=24124593; DOI=10.1371/journal.pone.0076773;
RA   Roca H., Hernandez J.R., Weidner S., McEachin R.C., Fuller D., Sud S.,
RA   Schumann T., Wilkinson J.E., Zaslavsky A., Li H.-W., Maher C.A.,
RA   Daignault-Newton S., Healy P.N., Pienta K.J.;
RT   "Transcription factors OVOL1 and OVOL2 induce the mesenchymal to
RT   epithelial transition in human cancer.";
RL   PLoS ONE 8:E76773-E76773(2013).
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RX   PubMed=25426557; DOI=10.18632/oncotarget.2766;
RA   Shiraishi T., Verdone J.E., Huang J., Kahlert U.D., Hernandez J.R.,
RA   Torga G., Zarif J.C., Epstein T., Gatenby R., McCartney A.,
RA   Elisseeff J.H., Mooney S.M., An S.S., Pienta K.J.;
RT   "Glycolysis is the primary bioenergetic pathway for cell motility and
RT   cytoskeletal remodeling in human prostate and breast cancer cells.";
RL   Oncotarget 6:130-143(2015).
//