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Cellosaurus PC3-EMT12 (CVCL_B0E4)

[Text version]
Cell line name PC3-EMT12
Accession CVCL_B0E4
Resource Identification Initiative To cite this cell line use: PC3-EMT12 (RRID:CVCL_B0E4)
Comments Population: Caucasian.
Characteristics: Transfected with a pLentilox-EV-Luc luciferase expression vector.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B0CB (PC3-epi)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=24124593; DOI=10.1371/journal.pone.0076773; PMCID=PMC3790720
Hernan Roca, James R. Hernandez, Savannah Weidner, Richard C. McEachin, David Fuller, Sudha Sud, Taibriana Schumann, John E. Wilkinson, Alexander Zaslavsky, Hang-Wen Li, Christopher A. Maher ...Show all 14 authors... , Stephanie Daignault-Newton, Patrick N. Healy, Kenneth James Pienta; Show fewer authors
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer.
PLoS ONE 8:e76773.1-e76773.20(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B0E4
Encyclopedic resources Wikidata; Q108821091
Gene expression databases GEO; GSM1063983
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number9