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Cellosaurus PC-12 HD-Q74 cell 1b (CVCL_AV00)

[Text version]
Cell line name PC-12 HD-Q74 cell 1b
Accession CVCL_AV00
Resource Identification Initiative To cite this cell line use: PC-12 HD-Q74 cell 1b (RRID:CVCL_AV00)
Comments Transfected with: HGNC; 4851; HTT (1st exon with 74-Q run).
Transfected with: UniProtKB; P42212; GFP.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH.
Hierarchy Parent: CVCL_0481 (PC12)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line

PubMed=11532992; DOI=10.1093/hmg/10.17.1829
Wyttenbach A., Swartz J., Kita H., Thykjaer T., Carmichael J., Bradley J., Brown R., Maxwell M., Schapira A.H.V., Orntoft T.F., Kato K., Rubinsztein D.C.
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.
Hum. Mol. Genet. 10:1829-1845(2001)

Cell line collections (Providers) Ximbio; 152417
Encyclopedic resources Wikidata; Q54938393
Entry history
Entry creation02-May-2016
Last entry update29-Jun-2023
Version number7