ID   PC-12 HD-Q74 cell 1b
AC   CVCL_AV00
DR   Wikidata; Q54938393
DR   Ximbio; 152417
RX   PubMed=11532992;
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4851; HTT (Note=1st exon with 74-Q run).
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
CC   Breed/subspecies: NEDH; RS=RS_0000603.
DI   NCIt; C121568; Rat adrenal gland pheochromocytoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0481 ! PC12
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 10-04-25; Version: 10
//
RX   PubMed=11532992; DOI=10.1093/hmg/10.17.1829;
RA   Wyttenbach, Andreas
RA   Swartz, Jina Elise
RA   Kita, Hiroko
RA   Thykjaer, Thomas
RA   Carmichael, Jenny
RA   Bradley, Jane
RA   Brown, Rosemary
RA   Maxwell, Michelle
RA   Schapira, Anthony Henry Vernon
RA   Orntoft, Torben Falck
RA   Kato, Kikuya
RA   Rubinsztein, David Chaim
RT   "Polyglutamine expansions cause decreased CRE-mediated transcription
RT   and early gene expression changes prior to cell death in an inducible
RT   cell model of Huntington's disease.";
RL   Hum. Mol. Genet. 10:1829-1845(2001).
//