ID   PC-12 HD-Q74 cell 1b
AC   CVCL_AV00
DR   Wikidata; Q54938393
DR   Ximbio; 152417
RX   PubMed=11532992;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 4851; HTT (Note=1st exon with 74-Q run).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
CC   Breed/subspecies: NEDH; RS=RS:0000603.
DI   NCIt; C121568; Rat adrenal gland pheochromocytoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0481 ! PC12
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 10-09-24; Version: 8
//
RX   PubMed=11532992; DOI=10.1093/hmg/10.17.1829;
RA   Wyttenbach A., Swartz J., Kita H., Thykjaer T., Carmichael J.,
RA   Bradley J., Brown R., Maxwell M., Schapira A.H.V., Orntoft T.F., Kato K.,
RA   Rubinsztein D.C.;
RT   "Polyglutamine expansions cause decreased CRE-mediated transcription
RT   and early gene expression changes prior to cell death in an inducible
RT   cell model of Huntington's disease.";
RL   Hum. Mol. Genet. 10:1829-1845(2001).
//