Cellosaurus logo
expasy logo

Cellosaurus HeLa-Mitotrap-GGA2-FKBP (CVCL_AR70)

[Text version]
Cell line name HeLa-Mitotrap-GGA2-FKBP
Accession CVCL_AR70
Resource Identification Initiative To cite this cell line use: HeLa-Mitotrap-GGA2-FKBP (RRID:CVCL_AR70)
Comments Population: African American.
Characteristics: Transfected with Mitotrap, a construct composed of the import signal of yeast TOM70, a YFP and the rapamycin-binding (FRB) domain from MTOR.
Transfected with: HGNC; 16064; GGA2 (tagged with the FKBP domain from FKBP1A).
Transfected with: HGNC; 3942; MTOR (with Met1_Arg2018del and Gln2114_Trp2549del = FRB).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AR66 (HeLa-Mitotrap)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages http://www.enterprise.cam.ac.uk/reagents/hela-mitotrap-cell-lines/

PubMed=22902756; DOI=10.1016/j.cub.2012.07.012
Hirst J., Borner G.H.H., Antrobus R., Peden A.A., Hodson N.A., Sahlender D.A., Robinson M.S.
Distinct and overlapping roles for AP-1 and GGAs revealed by the 'knocksideways' system.
Curr. Biol. 22:1711-1716(2012)

Cell line collections (Providers) Ximbio; 152429
Encyclopedic resources Wikidata; Q54882725
Entry history
Entry creation02-May-2016
Last entry update02-May-2024
Version number11