ID   HeLa-Mitotrap-GGA2-FKBP
AC   CVCL_AR70
DR   Wikidata; Q54882725
DR   Ximbio; 152429
RX   PubMed=22902756;
WW   Provider; Cambridge Enterprise; -; https://web.archive.org/web/20200923093418/http://www.enterprise.cam.ac.uk/reagents/hela-mitotrap-cell-lines/
CC   Population: African American.
CC   Characteristics: Transfected with Mitotrap, a construct composed of the import signal of yeast TOM70, a YFP and the rapamycin-binding (FRB) domain from MTOR.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:16064; GGA2 (Note=Tagged with the FKBP domain from FKBP1A).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3942; MTOR (Note=With p.Met1_Arg2018del and p.Gln2114_Trp2549del = FRB).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_AR66 ! HeLa-Mitotrap
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 10-04-25; Version: 14
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RX   PubMed=22902756; DOI=10.1016/j.cub.2012.07.012; PMCID=PMC3485558;
RA   Hirst, Jennifer
RA   Borner, Georg H.H.
RA   Antrobus, Robin
RA   Peden, Andrew A.
RA   Hodson, Nicola A.
RA   Sahlender, Daniela Andrea
RA   Robinson, Margaret Scott
RT   "Distinct and overlapping roles for AP-1 and GGAs revealed by the
RT   'knocksideways' system.";
RL   Curr. Biol. 22:1711-1716(2012).
//