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Cellosaurus KPC3 (CVCL_A9ZK)

[Text version]
Cell line name KPC3
Accession CVCL_A9ZK
Resource Identification Initiative To cite this cell line use: KPC3 (RRID:CVCL_A9ZK)
Comments Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Mouse pancreatic neoplasm (NCIt: C34035)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LSL-KrasG12D:LSL-Trp53R270H:Pdx1-Cre (KPC).
Hierarchy Children:
CVCL_A9ZL (KPC3-TRP1)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=30381448; DOI=10.1158/1535-7163.MCT-18-0679
Benonisson H., Altintas I., Sluijter M., Verploegen S., Labrijn A.F., Schuurhuis D.H., Houtkamp M.A., Verbeek J.S., Schuurman J., van Hall T.
CD3-bispecific antibody therapy turns solid tumors into inflammatory sites but does not install protective memory.
Mol. Cancer Ther. 18:312-322(2019)

PubMed=32690771; DOI=10.1136/jitc-2020-000772; PMCID=PMC7373331
Lau S.P., van Montfoort N., Kinderman P., Lukkes M., Klaase L., van Nimwegen M., van Gulijk M., Dumas J., Mustafa D.A.M., Lievense S.L.A., Groeneveldt C., Stadhouders R., Li Y., Stubbs A., Marijt K.A., Vroman H., van der Burg S.H., Aerts J., van Hall T., Dammeijer F., van Eijck C.H.J.
Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model.
J. Immunother. Cancer 8:e000772.1-e000772.14(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114430
Entry history
Entry creation29-Oct-2020
Last entry update10-Sep-2024
Version number5