ID   KPC3
AC   CVCL_A9ZK
DR   Wikidata; Q102114430
RX   PubMed=30381448;
RX   PubMed=32690771;
CC   Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
CC   Breed/subspecies: LSL-KrasG12D:LSL-Trp53R270H:Pdx1-Cre (KPC).
DI   NCIt; C34035; Mouse pancreatic neoplasm
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 10-09-24; Version: 5
//
RX   PubMed=30381448; DOI=10.1158/1535-7163.MCT-18-0679;
RA   Benonisson H., Altintas I., Sluijter M., Verploegen S., Labrijn A.F.,
RA   Schuurhuis D.H., Houtkamp M.A., Verbeek J.S., Schuurman J.,
RA   van Hall T.;
RT   "CD3-bispecific antibody therapy turns solid tumors into inflammatory
RT   sites but does not install protective memory.";
RL   Mol. Cancer Ther. 18:312-322(2019).
//
RX   PubMed=32690771; DOI=10.1136/jitc-2020-000772; PMCID=PMC7373331;
RA   Lau S.P., van Montfoort N., Kinderman P., Lukkes M., Klaase L.,
RA   van Nimwegen M., van Gulijk M., Dumas J., Mustafa D.A.M.,
RA   Lievense S.L.A., Groeneveldt C., Stadhouders R., Li Y., Stubbs A.,
RA   Marijt K.A., Vroman H., van der Burg S.H., Aerts J., van Hall T.,
RA   Dammeijer F., van Eijck C.H.J.;
RT   "Dendritic cell vaccination and CD40-agonist combination therapy
RT   licenses T cell-dependent antitumor immunity in a pancreatic carcinoma
RT   murine model.";
RL   J. Immunother. Cancer 8:e000772.1-e000772.14(2020).
//